We are focused on innovation of chemical purification, and industrial microbiology processes.
The complementarity of our competences, together with our strong industrial experience, ensures a valuable process definition.
We produce Dalbavancin, Teicoplanin, Anidulafungin, Ramoplanin, ECBN, Thermorubin, and Luminescent Microorganisms, custom reference standards upon request.
We are a leader company thanks to our state-of-the-art equipment and long experience in the field.
Our continuous commitment enables us to pursue the most critical goals for our clients.
Since our establishment we have been developing our processes employing cutting-edge technologies.
Recombinant DNA technology, design of experiments, flow chemistry are common tools employed at ACT
We understand the client’s needs and guarantee effective results in a timely manner. Our founding values, competences, accuracy and proactivity, make clients trust ACT
Most of our products are GMP compliant. All products have their own Batch Record. A new GMP Preparative High Pressure Chromatography Plant is under construction.
F. Beltrametti, A. Consolandi, L. Carrano, F. Bagatin, R. Rossi, L. Leoni, E. Zennaro, E. Selva, F. Marinelli. 2007. Resistance to glycopeptide antibiotics in the teicoplanin producer is mediated by van gene homologue expression directing the synthesis of a modified cell wall peptidoglycan. Antimicrob. Agents Chemother. 51: 1135-1141.16
G.L. Marcone, F. Beltrametti, E. Binda, L. Carrano, L. Foulston, A. Hesketh, M. Bibb, F. Marinelli. 2010. Novel mechanism of glycopeptide resistance in the A40926 producer Nonomuraea sp. ATCC 39727. Antimicrob. Agents Chemother. 54:2465-2472
F. Beltrametti, Barucco, D., Rossi, R., Selva, E., Marinelli, F. Protoplast fusion and gene recombination in the uncommon actinomycete Planobispora rosea producing GE2270. J. Antibiot. 2007;60(7):447-454
Di Palo, S., Gandolfi, R., Jovetic, S., Marinelli, F., Romano, D., Molinari, F. A new bacterial mannosidase for the selective modification of ramoplanin and its derivatives. Enzyme Microb Technol. 2007;41:806-811.
G.L. Marcone, L. Foulston, E. Binda, F. Marinelli, M. Bibb, F. Beltrametti. 2010. Methods for the genetic manipulation of Nonomuraea sp. ATCC 39727. J. Ind. Microbiol. Biotechnol. 37:1097-1103
G. L. Marcone, L. Carrano, F. Marinelli, F. Beltrametti. 2010. Protoplast preparation and reversion to the normal filamentous growth in antibiotic-producing uncommon actinomycetes. J Antibiot. 63:83-88